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KMID : 0860920110130010044
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Journal of the Korean Association EMG-Electrodiagnostic Medicine
2011 Volume.13 No. 1 p.44 ~ p.48
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A Stiff-Person Syndrome Misdiagnosed as Parkinson Syndrome in a Patient with Cerebral Palsy - A Case Report -
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Park Tae-Hyung
Kim Jong-Moon
Choi Young-Chil
Lee Jun-Ho
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Abstract
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Stiff-person syndrome (SPS) or Stiff-man syndrome (SMS) is a rare disorder characterized by progressive
muscle rigidity with painful spasm of axial and limb muscles causing impairment of voluntary movements
which precipitated by generally non-provocative stimulations such as tactile, auditory or emotional
stimulations. This symptoms might resembling chronic form of tetanus and can be misdiagnosed as
Parkinson’s syndrome, multiple sclerosis, fibromyalgia, psychosomatic illness, or anxiety and phobia. A
definitive diagnosis can be made with a serologic test that measures the level of glutamic acid decarboxylase
(GAD) antibodies in the blood and electromyographic findings.
In our case, we present a cerebral palsy patient with SPS which was misdiagnosed as Parkinson’s disease
at first impression.
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KEYWORD
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Stiff-person syndrome , Parkinson’s disease , Glutamic acid decarboxylase (GAD) antibodies
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